Studying How Premonitory Urges Change During Habit Reversal Training for Tics in Children and Teens
Led by University of Utah · Updated on 2025-05-28
6
Participants Needed
1
Research Sites
43 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating how premonitory urges PUs, which are uncomfortable sensations signaling an upcoming tic, change during Habit Reversal Training HRT for tics in children and adolescents aged 8 to 17. The study aims to understand whether these urges decrease within and between HRT sessions, which could provide insights into how tic symptoms improve and the mechanisms behind tic maintenance and reduction. This research is important because while tics can be reduced, it is unclear if the premonitory urges diminish alongside tic improvement.
Participants will undergo three therapist-guided HRT sessions, each lasting one hour, focusing on three specific tics. In addition to these sessions, participants will engage in 15 practice sessions over three weeks, each about 30 minutes, to practice competing responses learned during therapy. Both study visits and practice sessions will be conducted in person and online via secure videoconference, allowing flexibility in participation.
During the study, participants will attend a total of five study visits, including intake, treatment, and a post-assessment. Researchers will measure premonitory urge severity using an urge thermometer during baseline observations, each HRT session, practice sessions, and post-assessment. Tic frequency will also be counted during these times to assess changes. The study is designed to closely monitor fluctuations in urges and tic behaviors throughout treatment and practice, with sessions lasting from 1 to 1.5 hours and practice sessions around 30 minutes each.
CONDITIONS
Brief Title
Investigating Changes in Premonitory Urges During Habit Reversal Training for Tics
Research Team
E
Emily I Braley, MS
M
Michael Himle, PhD
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This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
Factors
Habit Reversal Training (HRT)
Supportive Psychotherapy
What it is
A behavioral therapy where participants learn to detect early signs of tics and practice competing responses to prevent or interrupt them. The approach uses therapist-led instruction and home practice.
A non-specific talk therapy that focuses on emotional support, psychoeducation, and general problem-solving without systematic behavioral techniques targeting tic control.
Role in study
The only behavioral intervention tested, administered to all enrolled participants in an open-label single-group format.
Not included as a study arm in this trial but serves as an established active comparator in other pediatric tic disorder trials.
Primary use
Designed to reduce tic severity and help participants manage premonitory urges by replacing tics with alternative behaviors.
Intended to provide psychological support and education to young people about tics without using specific techniques to suppress tics.
How it is given or performed
Delivered in therapist-led sessions where participants are taught to recognize urges and tics, then practice competing responses during sessions and at home.
Conducted in therapist-led sessions that focus on open discussion, emotional support, and general coping strategies rather than directive behavioral practice.
Evidence status
Well-supported by multiple randomized controlled trials and long-term studies showing reductions in tic severity and improved ability to manage tics in children and adolescents.
Does not significantly reduce tic severity based on randomized controlled comparisons with behavioral treatments; provides emotional support but lacks targeted tic reduction mechanisms.
Important limitations
Access to trained therapists can be limited and consistent home practice is required; not all participants may complete homework or show the same response.
Does not directly address tic suppression or urge awareness and is not associated with significant tic improvement compared to behavioral therapy.
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
Who Can Participate
Age: 8Years - 17Years
All Genders
Eligibility Criteria
You may qualify if you...
Participants must have a DSM-5-TR diagnosis of Tourette Disorder
Must have at least three motor and/or vocal tics and be interested in treatment
Experience a premonitory urge rated at least 4 out of 8 for each target tic
Targeted tics occur on average at least once per minute during a 10-minute observation
Aged between 8 and 17 years
No planned changes in medication initiation or dosage during study participation
You will not qualify if you...
Presence of comorbid conditions that interfere with treatment, such as unmanaged ADHD, OCD, or anxiety
Previous participation in more than two sessions of CBIT or HRT
Yale Global Tic Severity Score of 40 or higher, or 20 or higher for primary motor or vocal tic disorder
Tics suspected to be due to functional neurological symptom disorder according to DSM-5-TR criteria
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Outpatient Treatment
Duration - 3 weeks
Participants receive habit reversal training (HRT) involving 3 therapist-guided sessions and practice sessions to reduce tics by learning competing responses.
3 weekly therapist-guided sessions and 15 practice sessions during the week
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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Published Research Related To This Trial
The DIAMOND-KID: Psychometric Properties of a Structured Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders in Children and Adolescents.
David F Tolin, Kimberly S Sain, Elizabeth Davis...