Actively Recruiting
Investigating the Effects of Social Stress on Brain Imaging
Led by Massachusetts Institute of Technology · Updated on 2025-12-03
50
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
Sponsors
M
Massachusetts Institute of Technology
Lead Sponsor
M
Massachusetts General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to examine whether experiencing a social stressor prior to the collection of neuroimaging measures is associated with differences in brain activation in healthy participants.
CONDITIONS
Official Title
Investigating the Effects of Social Stress on Brain Imaging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability and willingness to provide written informed consent
- Sufficiently fluent in English to participate in the trial
- Between 18-55 years of age (inclusive)
- Right-hand dominant
- Current medications are stable for past 30 days (no changes to dose or frequency)
- Negative result on pregnancy test (if female)
- Negative result on urine drug screening
- Liebowitz Social Anxiety Scale (LSAS) less than 30
You will not qualify if you...
- History of bipolar disorder, schizophrenia, psychosis, or delusional disorders
- History of eating disorder within past 6 months
- History of any traumatic brain injury
- Currently diagnosed with diabetes mellitus
- Presence of severe medical illness that would prevent completion of study procedures
- Presence of significant neurological illness or cognitive dysfunction (e.g., seizures, dementia)
- History of substance use disorder within past 6 months (other than nicotine and caffeine)
- Use of any cannabis-containing products in past 30 days (CBD or THC)
- Use of benzodiazepines in past 2 weeks
- Use of alpha- or beta-blockers in the past week
- History of claustrophobia
- Contraindications for MRI (e.g., shrapnel)
- Presence of any other medical condition that, in the investigator's opinion, may interfere with the study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts Institute of Technology
Cambridge, Massachusetts, United States, 02139
Actively Recruiting
Research Team
O
Omar Rutledge, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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