Actively Recruiting
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
Led by Kessler Foundation · Updated on 2025-11-24
10
Participants Needed
1
Research Sites
534 weeks
Total Duration
On this page
Sponsors
K
Kessler Foundation
Lead Sponsor
K
Kessler Institute for Rehabilitation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, learning and memory, and walking abilities of individuals with multiple sclerosis who went through the traditional as compared to others who used the robotic exoskeleton as part of their therapy.
CONDITIONS
Official Title
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with multiple sclerosis.
- Have moderate to severe difficulty walking but still able to walk using the robotic exoskeleton.
- Have some difficulty with thinking and problem solving as determined by a screening test.
- Aged between 18 and 75 years.
- Free from MS symptom flare-ups for at least one month before testing.
- Able to maintain a constant level of spasticity medication during the study.
- Able to walk with or without assistive devices.
- English is the primary language.
- Physically fit to use the exoskeleton device: height between 60 and 76 inches, weight under 220 lbs.
- Able to tolerate standing upright for 30 minutes with assistance if needed.
- Have normal joint range of motion for walking.
- Have sufficient strength to use a hemiwalker, bilateral canes, or walker while wearing the exoskeleton.
- Have stable blood pressure.
- Willing and able to give informed consent.
- Able and willing to follow study procedures, instructions, and follow-up requirements.
You will not qualify if you...
- History of head injury, stroke, seizures, or other major neurological conditions besides MS.
- Severe difficulty in thinking and problem solving preventing participation.
- Currently taking steroids, benzodiazepines, antipsychotics, or neuroleptics.
- Pregnant.
- Completely reliant on a wheelchair.
- Joint contracture or spasticity limiting normal walking range of motion.
- Skin issues preventing wearing the robotic exoskeleton.
- Pressure sores stage 2 or higher affecting weight bearing or device fit.
- Orthopedic issues or history interfering with walking or joint motion (e.g., knee replacement).
- Recent hospitalization for heart attack, heart surgery, or acute heart failure within 3 months.
- Other medical conditions affecting ability to use the robotic device.
- Have pacemaker, implanted electrical devices, brain stimulator, aneurysm clips, metallic prostheses, permanent eyeliner, implanted pumps, or shrapnel fragments.
- Dental implants requiring discussion with investigators.
- Doctor has advised against having a regular MRI as part of medical care.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kessler Foundation
West Orange, New Jersey, United States, 07052
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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