Actively Recruiting
Investigating Epilepsy: Screening and Evaluation
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2026-06-03
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying epilepsy in both adults and children aged 8 years and older who have a diagnosed or suspected form of the condition. The goal is to learn more about seizures and how best to treat people with epilepsy that does not respond well to medication. This observational study aims to maintain a group of patients with epilepsy to support ongoing NIH epilepsy research and to observe the natural course of epilepsy and related disorders. Participants receive standard evaluations and care, including physical exams, medical history reviews, and questionnaires. They may be admitted to the hospital for several weeks during which their medications might be adjusted or stopped. Various tests are conducted, such as blood and urine tests, EEGs (brain wave recordings with attached wires), memory and thinking assessments, MRI scans, MEG brain recordings using a helmet, and PET scans involving a small radioactive dye injection. During the study, participants will have many visits and assessments to monitor their condition and treatment. Follow-up may continue at intervals, and participation ends if they have not been seen clinically for their epilepsy for three years. The research team measures outcomes like screening and characterizing drug-resistant epilepsy cases over a five-year period, and clinical care data is used for descriptive and correlational research. The total participation time varies by individual needs.
CONDITIONS
Brief Title
Investigating Epilepsy: Screening and Evaluation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 8 years or older
- Known or suspected diagnosis of epilepsy
- Ability to give informed consent or have a legally authorized representative able to give consent
- If unable to give informed consent, ability to give verbal assent
You will not qualify if you...
- Unstable medical conditions that make participation unsafe or interfere with compliance
- Unable to travel to the NIH for study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 5 years
Participants are followed over time to observe the natural history of epilepsy and related disorders, with data collected through clinical care.
Visits occur as part of standard clinical care
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
A
Aaliyah M HamidullahThiam
Y
Yasser Tajali, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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