Actively Recruiting
Led by The University of Texas Health Science Center, Houston · Updated on 2026-05-04
225
Participants Needed
1
Research Sites
26 weeks
Total Duration
T
The University of Texas Health Science Center, Houston
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
This research aims to understand how different factors at the provider and clinic levels affect the success of strategies led by facilitators to increase healthcare providers' recommendations and vaccination rates for Human Papillomavirus (HPV) among Latino/a adolescents. The study focuses on nine Federally Qualified Health Centers (FQHCs) with a high Latino adolescent population, evaluating the sustainability and impact of these facilitator-driven strategies over time. The study involves a facilitator who works with healthcare providers and immunization navigators at each clinic using four key strategies: provider education modules, development of a clinical practice plan, training of immunization navigators to carry out the plan, and providing ongoing technical assistance with assessment and feedback. Clinics are randomized into three groups with staggered timing for control and intervention phases lasting from 15 to 27 months for control and 18 to 30 months for intervention periods. Participants include providers, staff, and parents of adolescent patients at each clinic. Researchers will measure HPV vaccination rates, such as the percentage of adolescents receiving the first and second doses before specific birthday milestones, along with uptake of other vaccines like Tdap and MenACWY. Data will be collected from baseline through about 60 months to assess the effect of the implementation strategies, with regular monitoring and feedback to support adherence and sustainability.
CONDITIONS
Investigating Facilitator-driven, Multi-level Implementation Strategies in Federally Qualified Health Centers to Improve Provider Recommendation and HPV Vaccination Rates Among Latino/a Adolescents
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 15 to 27 months depending on clinic assignment
Participants are observed during a control period without intervention to establish baseline vaccination rates.
Periodic visits as part of routine healthcare
Duration - 18 to 30 months depending on clinic assignment
Participants experience a multi-level implementation strategy including provider education, clinical practice planning, staff training, and ongoing technical assistance to improve HPV vaccination rates.
Ongoing engagement with healthcare providers and staff throughout the intervention period
Duration - Up to the end of study at about 60 months from baseline
Participants are monitored for vaccination outcomes and continued assessment after the implementation phase.
Assessments occur during routine visits as part of clinical care
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
D
Daisy Y Morales-Campos, PhD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
3
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Daisy Y Morales-Campos, Prajakta Adsul, Yuanyuan Liang...
https://pubmed.ncbi.nlm.nih.gov/40205591