Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07130513

Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions

Led by University of Glasgow · Updated on 2025-10-02

30

Participants Needed

2

Research Sites

49 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will recruit 30 adults (men and women, aged 18 years and over) who will be randomly assigned to one of two groups in a 12-week double-blind pilot trial. Participants will receive either: * Arm 1: Krill Oil group: 4 g/day of krill oil supplements (Superba™ Antarctic Krill Oil, 1000 mg capsules), or * Arm 2: Control group: 4 g/day of placebo (vegetable oil capsules). Participants will be instructed to maintain their usual diet and physical activity patterns throughout the study. Eligibility will be assessed using a health screening questionnaire, completed with the researcher's assistance, before obtaining informed consent. Habitual physical activity will be evaluated using the International Physical Activity Questionnaire (short form), and dietary intake will be assessed with the EPIC Food Frequency Questionnaire (FFQ) at both the beginning and end of the study. In addition, participants will record their fish consumption weekly using a dedicated logbook. Measurements will be taken at baseline and after 12 weeks, including: * Blood samples to assess inflammatory and metabolic markers. * Anthropometry and body composition, including weight, height, fat mass, fat percentage, and muscle mass (via ultrasound). * Muscle strength, measured using handgrip strength and maximal voluntary contraction (each performed three times with rest between attempts). * Physical performance, assessed with a 4-meter walk test at normal speed Upon completing the study, participants will receive a £50 voucher in appreciation of their contribution.

CONDITIONS

Official Title

Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 18 years and older
  • Have one or more high-risk long-term conditions, including rheumatoid arthritis, gout, type 2 diabetes, coronary heart disease, or stroke (including transient ischemic attack)
Not Eligible

You will not qualify if you...

  • Diagnosed with and currently treated for any type of cancer
  • Have neurocognitive disorders or health conditions affecting memory, such as Alzheimer's disease or dementia
  • Have aortic stenosis, history of haemorrhagic stroke, or aneurysms
  • Currently undergoing anticoagulant therapy
  • Use muscle mass supplements or are pregnant or breastfeeding
  • Have a history of allergy to fish or fish oil
  • Regularly consume more than one portion of oily fish per week or use fish oil or krill oil supplements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Lab 242, Sir James Black Building, University of Glasgow

Glasgow, Lanarkshire, United Kingdom, G12 8TA

Actively Recruiting

2

University of Glasgow

Glasgow, Lanarkshire, United Kingdom, G12 8TA

Not Yet Recruiting

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Research Team

P

Professor Stuart Gray

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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