Actively Recruiting
Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions
Led by University of Glasgow · Updated on 2025-10-02
30
Participants Needed
2
Research Sites
49 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will recruit 30 adults (men and women, aged 18 years and over) who will be randomly assigned to one of two groups in a 12-week double-blind pilot trial. Participants will receive either: * Arm 1: Krill Oil group: 4 g/day of krill oil supplements (Superba™ Antarctic Krill Oil, 1000 mg capsules), or * Arm 2: Control group: 4 g/day of placebo (vegetable oil capsules). Participants will be instructed to maintain their usual diet and physical activity patterns throughout the study. Eligibility will be assessed using a health screening questionnaire, completed with the researcher's assistance, before obtaining informed consent. Habitual physical activity will be evaluated using the International Physical Activity Questionnaire (short form), and dietary intake will be assessed with the EPIC Food Frequency Questionnaire (FFQ) at both the beginning and end of the study. In addition, participants will record their fish consumption weekly using a dedicated logbook. Measurements will be taken at baseline and after 12 weeks, including: * Blood samples to assess inflammatory and metabolic markers. * Anthropometry and body composition, including weight, height, fat mass, fat percentage, and muscle mass (via ultrasound). * Muscle strength, measured using handgrip strength and maximal voluntary contraction (each performed three times with rest between attempts). * Physical performance, assessed with a 4-meter walk test at normal speed Upon completing the study, participants will receive a £50 voucher in appreciation of their contribution.
CONDITIONS
Official Title
Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women aged 18 years and older
- Have one or more high-risk long-term conditions, including rheumatoid arthritis, gout, type 2 diabetes, coronary heart disease, or stroke (including transient ischemic attack)
You will not qualify if you...
- Diagnosed with and currently treated for any type of cancer
- Have neurocognitive disorders or health conditions affecting memory, such as Alzheimer's disease or dementia
- Have aortic stenosis, history of haemorrhagic stroke, or aneurysms
- Currently undergoing anticoagulant therapy
- Use muscle mass supplements or are pregnant or breastfeeding
- Have a history of allergy to fish or fish oil
- Regularly consume more than one portion of oily fish per week or use fish oil or krill oil supplements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Lab 242, Sir James Black Building, University of Glasgow
Glasgow, Lanarkshire, United Kingdom, G12 8TA
Actively Recruiting
2
University of Glasgow
Glasgow, Lanarkshire, United Kingdom, G12 8TA
Not Yet Recruiting
Research Team
P
Professor Stuart Gray
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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