Actively Recruiting
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma
Led by Medical University of Vienna · Updated on 2025-05-23
300
Participants Needed
1
Research Sites
452 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There is increasing evidence that there are genetic risk factors for several forms of glaucoma, such as glaucoma caused by pseudoexfoliation syndrome (PXF) ,primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG). The aim of the present prospective, multi-center, case-control study is to identify susceptibility genes/loci for PXF, PACG and POAG using a whole genome association (WGA) approach.
CONDITIONS
Official Title
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with confirmed pseudoexfoliation syndrome (exfoliation glaucoma or pseudoexfoliation of the lens) and age 50 years or more
- Patients with confirmed acute primary angle closure or primary angle closure glaucoma and age 21 years or more
- Healthy controls with no evidence of PXF, glaucoma, uveitis, or major ocular disease and age over 60 years
- Patients with confirmed primary open angle glaucoma without exfoliation or pigment glaucoma and age 30 years or more
- Informed consent obtained
You will not qualify if you...
- Patients with neovascular glaucoma
- Patients with active or history of uveitis
- Patients with secondary angle closure such as neovascular glaucoma or uveitis/inflammatory eye disease
- Inability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Clinical Pharmacology, Medical University of Vienna
Vienna, Austria, 1090
Actively Recruiting
Research Team
G
Gerhard Garhöfer
CONTACT
D
Doreen Schmidl
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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