Actively Recruiting
Investigating Inhibitory Control Networks in Parkinson's Disease
Led by University of Alabama at Birmingham · Updated on 2025-12-02
140
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
Sponsors
U
University of Alabama at Birmingham
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
CONDITIONS
Official Title
Investigating Inhibitory Control Networks in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Eligible for surgery based on multi-disciplinary consensus review
- Have a diagnosis of Parkinson's disease or Essential Tremor
- Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
- Willingness to participate in the paradigms described in the protocol
You will not qualify if you...
- Inability to provide full and informed consent
- Age younger than 18
- Are not able to participate in study-related activities
- History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35233
Actively Recruiting
Research Team
N
Nicole Bentley, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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