Actively Recruiting
Investigating Neurocognitive Disorders Epidemiology
Led by King Chulalongkorn Memorial Hospital · Updated on 2024-04-22
990
Participants Needed
1
Research Sites
626 weeks
Total Duration
On this page
Sponsors
K
King Chulalongkorn Memorial Hospital
Lead Sponsor
H
Health Systems Research Institute,Thailand
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a prospective cohort study with the main purpose of predicting progression neurocognitive disorders in Thai population. The main predictor variables to be evaluated are plasma phosphorylated tau (p-tau) level and cognitive test scores, which will be combined using statistical/computational modeling. Additionally, it seeks to evaluate biomarkers for diagnosing disease pathologies, understand their correlation with clinical outcomes, and explore the socioeconomic impact of neurocognitive disorders. The study invites both participants for biospecimen collection, structured interviews, and cognitive examinations and schedules follow-up visits annually or biennially.
CONDITIONS
Official Title
Investigating Neurocognitive Disorders Epidemiology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be cognitively healthy with normal cognitive test results or have mild cognitive impairment or dementia confirmed by objective cognitive tests.
- For dementia participants, symptoms must begin before or after age 65 as identified by a physician.
- Meet criteria for dementia per NIA-AA or major neurocognitive disorder per DSM-5 for dementia groups.
- Be able to speak and understand Thai without a translator.
You will not qualify if you...
- Have significant neurological or uncontrolled psychiatric illness.
- Have significant unstable systemic conditions or end-stage organ failure that affect study participation.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
King Chulalongkorn Memorial Hospital
Pathum Wan, Bangkok, Thailand, 10330
Actively Recruiting
Research Team
P
Poosanu Thanapornsangsuth, M.D.
CONTACT
T
Thanakit Pongpitakmetha, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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