Actively Recruiting
Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia
Led by University of Surrey · Updated on 2024-04-24
132
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
U
University of Surrey
Lead Sponsor
A
American Society of Hematology
Collaborating Sponsor
AI-Summary
What this Trial Is About
This randomised control clinical trial aims to investigate the effects of exercise training and diet on physical and functional fitness and immunological and metabolic changes in adults with chronic lymphocytic leukaemia. Investigators will randomise participants to either 12 weeks of supervised/semi-supervised exercise only, exercise + nutritional guidance, or no exercise.
CONDITIONS
Official Title
Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of CLL (including small lymphocytic leukaemia) as per the International Workshop on CLL Guidelines
- Male or female 18 years of age or older
- Able to walk on a treadmill or cycle on an ergometer
- Pass the Physical Activity Readiness Questionnaires (PAR-Q and PAR-Q+)
You will not qualify if you...
- Started corticosteroid therapy less than 7 days before study entry (Prednisone 10mg or less or equivalent allowed; topical or inhaled corticosteroids permitted)
- Secondary cancer within 3 years needing treatment, except certain treated skin, cervical, bladder, or prostate cancers
- Absolute exercise contraindications such as recent serious heart events, unstable angina, uncontrolled arrhythmias, symptomatic aortic stenosis, symptomatic heart failure, acute pulmonary embolus, myocarditis, pericarditis, dissecting aneurysm, or acute infection
- Significant orthopedic limitations or musculoskeletal injuries restricting physical activity
- Type I diabetes, uncontrolled Type II diabetes, or chronic obstructive pulmonary disease
- Uncontrolled blood pressure (≥180/90) at rest
- Known HIV, Hepatitis B or Hepatitis C infection
- Unable to follow study requirements
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Surrey
Guildford, United Kingdom, GU2 7WG
Actively Recruiting
Research Team
D
David Bartlett, PhD
CONTACT
E
Ellie Miles
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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