Screening for fetal growth restriction.
Suneet P Chauhan, Everett F Magann
https://pubmed.ncbi.nlm.nih.gov/16721107Actively Recruiting
Age: 16Years - 60Years
FEMALE
Healthy Volunteers
ID03662178
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth (Oxford Growth Restriction Identification Programme (OxGRIP)) on Risk Factors for and the Incidences of Adverse Maternal, Fetal and Neonatal Outcome
Led by Oxford University Hospitals NHS Trust · Updated on 2026-01-29
56000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Fetal growth restriction during pregnancy is a major risk factor for stillbirth, with many stillbirths linked to problems in fetal growth. Detecting growth-restricted babies before birth is important to monitor their health and decide the best time for delivery. However, routine detection rates have been low in NHS England, with only about 25% of growth-restricted babies identified before birth. Oxford University Hospitals NHS Foundation Trust, in partnership with Oxford Academic Health Science Network, developed the Oxford Growth Restriction Pathway (OxGRIP) to improve detection and outcomes for these at-risk babies while using resources efficiently and reducing unnecessary interventions. The OxGRIP pathway includes a routine ultrasound scan at 36 weeks gestation for all pregnant women. Additional growth scans are performed at 28 and 32 weeks based on risk factors and a universal uterine artery Doppler scan at 20 weeks. The pathway also evaluates other ultrasound measures linked to poor outcomes, such as growth velocity and blood flow in key arteries. This pathway combines several care elements previously not used together and aims to improve clinical outcomes and resource use. This study uses only routinely collected clinical data, with no direct patient participation needed. Researchers analyze data from pregnancies cared for at Oxford University Hospitals between 2013 and 2019 to assess how the OxGRIP pathway affects perinatal mortality and other maternal, fetal, and neonatal outcomes. They also look at ultrasound markers, clinical complications like hypertension and diabetes, birth details, and neonatal health. The study provides valuable information on the benefits and impacts of this structured ultrasound scanning approach over several years.
CONDITIONS
Brief Title
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Who Can Participate
Age: 16Years - 60Years
FEMALE
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Pregnant women receiving antenatal care at Oxford University Hospitals NHS Foundation Trust from January 2013 to December 31, 2019
- Female
- Aged between 16 and 60 years
- No exclusion criteria apply
You will not qualify if you...
- Women who have opted out of pregnancy-related research during this pregnancy while receiving care at Oxford University Hospitals NHS Foundation Trust
- Women whose labor and delivery care takes place outside Oxford University Hospitals NHS Foundation Trust
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Data is collected from routine clinical care without additional visits.
Diagnostic Evaluation
Duration - Up to 7 years depending on data collection period
Participants undergo ultrasound scanning and other antenatal assessments as part of routine care to monitor fetal growth and risk factors.
Ultrasound scans and antenatal assessments occur as part of routine healthcare visits.
Long-term Monitoring
Duration - Up to 7 years depending on data collection period
Participants' clinical outcomes during pregnancy, birth, and postnatal periods are observed through routinely collected clinical data.
Outcomes are monitored via routine healthcare records without additional visits.
Trial Site Locations
Total: 1 location
1
Oxford University Hospitals NHS Foundation Trust
Oxford, Oxfordshire, United Kingdom, OX3 9DU
Actively Recruiting
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Research Team
L
Lawrence Impey
C
Christina Aye
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Ulla Sovio, Ian R White, Alison Dacey...
https://pubmed.ncbi.nlm.nih.gov/26360240Antenatal care, identification of suboptimal fetal growth and risk of late stillbirth: findings from the Auckland Stillbirth Study.
Tomasina Stacey, John M D Thompson, Edwin A Mitchell...
https://pubmed.ncbi.nlm.nih.gov/22276935International standards for early fetal size and pregnancy dating based on ultrasound measurement of crown-rump length in the first trimester of pregnancy.
A T Papageorghiou, S H Kennedy, L J Salomon...
https://pubmed.ncbi.nlm.nih.gov/25044000Maternal and fetal risk factors for stillbirth: population based study.
Jason Gardosi, Vichithranie Madurasinghe, Mandy Williams...
https://pubmed.ncbi.nlm.nih.gov/23349424