Actively Recruiting
Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
Led by Rutgers, The State University of New Jersey · Updated on 2026-05-04
16
Participants Needed
2
Research Sites
276 weeks
Total Duration
On this page
Sponsors
R
Rutgers, The State University of New Jersey
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial investigates the nutrients pancreatic cancers depend on in which to survive and the processes these tumors use (metabolism) to obtain these nutrients. Giving U-13C-glucose during surgery may allow doctors to trace the metabolic activity of pancreatic cancer in research experiments done in the laboratory. These experiments may help researchers understand how cancer cells manage their nutrients when compared to normal pancreatic cells.
CONDITIONS
Official Title
Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients 18 years of age or older
- Diagnosed with pancreatic adenocarcinoma by biopsy
- Candidates for planned surgical removal of the tumor with or without prior chemotherapy
- Willing to undergo small biopsies of tumor and normal tissue during surgery for research
- Able to understand the investigational nature of the study and provide written informed consent
- Study will enroll 16 patients: 8 without prior treatment and 8 with at least 3 months of neoadjuvant chemotherapy
You will not qualify if you...
- Receiving any anti-cancer therapy other than chemotherapy before surgery (such as immunotherapy or biologic therapy)
- Currently enrolled or planning to enroll in another clinical study involving investigational treatments during this study
- Having another active cancer at the same time
- Of child-bearing potential without a recent negative pregnancy test done outside this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Cooperman Barnabas Medical Center (Saint Barnabas Medical Center)
Livingston, New Jersey, United States, 07039
Actively Recruiting
2
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, United States, 08903
Actively Recruiting
Research Team
H
Howard Hochster, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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