Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06375278

Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation

Led by Restorear Devices LLC · Updated on 2024-11-21

54

Participants Needed

1

Research Sites

96 weeks

Total Duration

On this page

Sponsors

R

Restorear Devices LLC

Lead Sponsor

U

University of Miami

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia for preservation of residual hearing in cochlear implant surgery. The main questions the trial aims to answer are: 1. Is mild therapeutic hypothermia safe for use during cochlear implantation? 2. Is mild therapeutic hypothermia effective at preserving residual hearing after cochlear implantation? Participants will receive mild therapeutic hypothermia therapy during cochlear implant surgery. Researchers will compare results from those receiving the therapy to those from a control group (individuals receiving no therapy).

CONDITIONS

Official Title

Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years and older
  • Diagnosed with severe to profound sensorineural hearing loss
  • Planning to undergo cochlear implantation at the University of Miami
  • Equal number of men and women participants
  • Residual hearing confirmed by pre-surgical auditory brainstem response (ABR) for efficacy study
  • Patients receiving cochlear implant devices from any of the three manufacturers
  • English or Spanish speakers
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Not meeting functional hearing requirements
  • Receiving cochlear implant devices not approved or listed by the study manufacturers (Advanced Bionics, Cochlear Corporation, Med-EL) unless manufacturer criteria change

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Miami

Miami, Florida, United States, 33136

Actively Recruiting

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Research Team

S

Suhrud M Rajguru, Ph.D.

CONTACT

C

Curtis S King

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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