Actively Recruiting
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
Led by Aalborg University · Updated on 2023-12-20
30
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: * To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep. In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: * To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep deprivation.
CONDITIONS
Official Title
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy men and women
- Aged 18 to 60 years
- Speak and understand English
- Have access to a smartphone during the experimental nights
You will not qualify if you...
- Pregnancy or lactation
- Drug addiction including any use of cannabis, opioids, or other drugs
- History or current neurological, dermatological, immunological, musculoskeletal, cardiac, or mental illnesses that may affect results (e.g., neuropathy, muscular pain in upper extremities, anxiety, depression, schizophrenia)
- Moles, wounds, scars, or tattoos in the treatment or test areas
- Current use of medications that could affect the trial such as antihistamines or painkillers
- Skin diseases
- Consumption of alcohol or painkillers 24 hours before and during study days
- Acute or chronic pain and itch
- Participation in other trials within 1 week before study entry (4 weeks for pharmaceutical studies)
- Inability to cooperate
AI-Screening
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Trial Site Locations
Total: 1 location
1
Aalborg University
Aalborg, Denmark, 9620
Actively Recruiting
Research Team
K
kristian KS Petersen
CONTACT
S
Silvia Lo Vecchio
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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