Actively Recruiting

Age: 18Years +
All Genders
NCT07506356

Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors

Led by University Hospital, Geneva · Updated on 2026-04-01

38

Participants Needed

1

Research Sites

39 weeks

Total Duration

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AI-Summary

What this Trial Is About

Treatment with semaglutide slows down gastric emptying , food remains in the stomach for a longer period of time. This slowing has important implications for anesthesia management. At present, we do not know the optimal duration for discontinuing this medication before surgery and anesthesia to ensure an empty stomach. This is an observational research project, conducted exclusively at the Geneva University Hospitals (HUG). To answer the research question, participation of 38 individuals will be required. The duration of participation for each person is 7 days. To recruit the necessary number of participants, approximately 1.5 years will be needed. This project is being carried out in accordance with Swiss legal requirements and recognized international guidelines. The competent ethics committee has reviewed and approved this project. The project will last 7 day during which the participants will need to come 3 times at the hospital to make gastric ultrasounds. On these days the participants will be asked to have a breakfast between 7 and 8 am including a minimum of bread and/or cereals and/or proteins. After that the participants will be asked to fast for 6 hours for solide food and 2 hours for liquids. If the participants smokes, they must for 12h before the exam. At 2Pm an anesthesiologist will welcome the participant to make the exam at the hospital to evaluate the gastric volume after what the participants will be able to get a small collation and go back home.

CONDITIONS

Official Title

Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Female or male aged 18 years or older
  • Diagnosed with type 2 diabetes
  • Treated with GLP-1 analog for more than 3 months
  • Signed informed consent
  • ASA physical status classification between I and IV
Not Eligible

You will not qualify if you...

  • Currently using insulin treatment
  • Have gastrointestinal motility disorders
  • Have had past gastric surgery
  • Have hiatal hernia
  • Experienced recent trauma
  • Unable to lie down for the exam
  • Unable to follow exam instructions due to language or dementia
  • Have a body mass index (BMI) greater than 40
  • Unable to stop smoking 12 hours before the measurements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpitaux Universitaires de Genève

Geneva, Canton of Geneva, Switzerland, 1211

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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