Study of Gastric Emptying Using Ultrasound in Adults with Type 2 Diabetes Treated with GLP-1 Receptor Agonists

What this Trial Is About

Researchers are investigating how semaglutide, a medication used for type 2 diabetes, affects the time food stays in the stomach and its implications for anesthesia management. The study focuses on determining the optimal time to stop this medication before surgery to ensure the stomach is empty. This observational research is conducted at the Geneva University Hospitals and involves 38 participants with type 2 diabetes treated with GLP-1 receptor agonists. Participants will take part in a 7-day study period during which they will visit the hospital three times for gastric ultrasounds. On each visit day, participants will eat a breakfast that includes bread, cereals, or proteins between 7 and 8 am, then fast for 6 hours from solid food and 2 hours from liquids before the ultrasound. Smokers must abstain from smoking for 12 hours before the exam. An anesthesiologist will perform the gastric ultrasound at 2 pm to evaluate the gastric volume. During the study, participants will undergo ultrasound assessments to measure stomach content after fasting periods. Researchers will monitor gastric volume to understand safe fasting times for anesthesia in diabetic patients treated with GLP-1 analogs. The study aims to provide information about gastric emptying 7 days after the last medication injection. Participation involves hospital visits for tests, and the study is approved by the relevant ethics committee and follows international guidelines.

Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors