Actively Recruiting

Age: 18Years - 65Years
FEMALE
Healthy Volunteers
NCT07294014

Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema

Led by Marmara University · Updated on 2026-01-02

32

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined. This case-control study aims to investigate whether patients with lipedema exhibit a higher prevalence of generalized joint hypermobility and foot structural abnormalities-specifically pes planus-compared with age- and BMI-matched controls. Using radiographic measurements (Meary angle and calcaneal inclination angle), clinical hypermobility assessment, and validated functional scales, the study seeks to determine the relationship between lipedema, hypermobility, and foot function.

CONDITIONS

Official Title

Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema

Who Can Participate

Age: 18Years - 65Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female participants
  • Age 18 years or older
  • Able to read and write
  • Availability of bilateral lateral foot radiographs obtained within the past 1 year
  • Willing and able to provide written and verbal informed consent
  • Clinical diagnosis of lipedema according to Halk and Damstra criteria (for lipedema group)
  • Female patients with nonspecific foot pain and similar age and BMI as lipedema group (for control group)
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Illiteracy
  • Inability or unwillingness to provide written and verbal informed consent
  • History of lower extremity fracture, trauma, or orthopedic surgery
  • Diagnosis of diabetes mellitus
  • Known rheumatologic disease
  • Known polyneuropathy or peripheral nerve injury affecting the lower extremities

AI-Screening

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Trial Site Locations

Total: 1 location

1

Marmara University Pendik Training and Research Hospital

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

G

Gökçenur Yalçın, M.D., PMR Specialist

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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