Actively Recruiting
Investigation of a New Window Into Intracranial Pressure: Venous Occlusion Pressure of the Isolated Periorbital Vein
Led by University of Freiburg · Updated on 2025-07-08
10
Participants Needed
1
Research Sites
35 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Elevated intracranial pressure (ICP) occurs when pressure inside the skull rises above normal levels, potentially leading to brain damage or herniation. Monitoring ICP is critical for managing conditions like brain tumors, traumatic brain injury, and stroke. Current ICP monitoring methods are invasive and carry risks, including infection and brain damage. For less severe cases, lumbar puncture is a safer, less invasive alternative. This study explores the potential of a non-invasive method, using venous pressure near the eye, to estimate ICP. The goal is to assess whether the results from this non-invasive approach are similar to the invasive lumbar CSF pressure measurements.
CONDITIONS
Official Title
Investigation of a New Window Into Intracranial Pressure: Venous Occlusion Pressure of the Isolated Periorbital Vein
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Medical indication to perform routine craniospinal CSF dynamic testing according to standard operative procedures
- Aged 18 to 95 years
- Willing and able to provide valid signed informed consent
You will not qualify if you...
- Known ongoing or history of abnormal cerebrospinal fluid communication
- Prior intervention for cerebrospinal fluid diversion
- Acute brain damage within the preceding 6 months
- Transdural surgery within the preceding 6 months
- Head wounds or hematoma that could hinder access to measurement site
- Any known pathological condition linked to the orbital socket influencing venous outflow
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Klinik für Neurochirurgie, Universitätsklinikum Freiburg
Freiburg im Breisgau, Germany
Actively Recruiting
Research Team
K
Katharina Wolf
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here