Actively Recruiting

Age: 20Years +
All Genders
NCT06648057

Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus Pembrolizumab

Led by CHA University · Updated on 2026-03-18

100

Participants Needed

1

Research Sites

118 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to evaluate the clinical efficacy and safety of lenvatinib plus pembrolizumab combination therapy in patients with advanced biliary tract cancer (BTC). This study aims to identify potential biomarkers that may predict treatment response by analyzing genetic data from blood and tissue samples. The study will focus on real-world clinical outcomes and the exploratory discovery of biomarkers associated with the efficacy of this treatment regimen.

CONDITIONS

Official Title

Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus Pembrolizumab

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with histologically or cytologically confirmed advanced biliary tract cancer.
  • Patients scheduled to receive Lenvatinib + Pembrolizumab for the treatment of advanced biliary tract cancer.
  • ECOG performance status of 0-2.
  • Patients aged 20 years or older at the time of treatment initiation.
  • Patients who understand and consent to participate in this study, and agree to provide samples obtained during the examination process.
Not Eligible

You will not qualify if you...

  • Patients who do not consent to participate in the study or withdraw their consent.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Bundang CHA Medical Center

Seongnam-si, Gyeonggi-do, South Korea, 13496

Actively Recruiting

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Research Team

H

Hong Jae Chon, MD. PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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