Actively Recruiting

Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07421960

Investigation of the Relationship Between Periodontitis and Sleep Quality

Led by Uskudar University · Updated on 2026-02-19

48

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project aims to investigate the relationship between periodontitis and sleep quality. Its originality lies in evaluating the association between periodontal status and sleep quality together with salivary interleukin-6 (IL-6), interleukin-6 (IL-10) IL-10, and pentraxin-3 levels. In particular, examining the relationship of sleep quality with biological, psychological, and lifestyle factors through periodontitis and salivary IL-6, IL-10, and pentraxin-3 levels has not been previously studied in the literature. Methodologically, periodontal status will be determined through clinical examination; participants' Pittsburgh Sleep Quality Index and Multidimensional Fatigue Inventory scores will be recorded; and salivary IL-6, IL-10, and pentraxin-3 levels will be measured. The obtained data will be compared using statistical analyses to determine the strength of the relationship between periodontitis severity and sleep quality. From a management perspective, the project will be conducted following approval from the ethics committee. In terms of broader impact, the results are expected to scientifically demonstrate the relationship between periodontitis and sleep quality, contribute to the adoption of a holistic health approach in clinical practice, and increase public health awareness. Additionally, the project is expected to provide a foundation for future research on the relationship between oral health and quality of life.

CONDITIONS

Official Title

Investigation of the Relationship Between Periodontitis and Sleep Quality

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be systemically healthy
  • Have a clinical diagnosis of periodontitis
  • Have a clinical diagnosis of periodontal health
Not Eligible

You will not qualify if you...

  • Regular use of systemic antibiotics, anti-inflammatory, or antioxidant drugs in the past 6 months
  • Nonsurgical periodontal treatment in the past 6 months
  • Surgical periodontal treatment in the past 12 months
  • Have fewer than 20 teeth
  • Current use of medications affecting gum health such as calcium channel blockers, phenytoin, cyclosporine, or hormone replacement therapy
  • Diagnosis of diabetes or rheumatoid arthritis
  • Pregnancy, lactating, or excessive alcohol consumption

AI-Screening

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Trial Site Locations

Total: 1 location

1

Uskudar University

Istanbul, Istanbul, Turkey (Türkiye), 34764

Actively Recruiting

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Research Team

A

Ayşegül Ayça Sarıkaya, Principal Investigator

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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