The S-LANSS score for identifying pain of predominantly neuropathic origin: validation for use in clinical and postal research.
Michael I Bennett, Blair H Smith, Nicola Torrance...
https://pubmed.ncbi.nlm.nih.gov/15772908Actively Recruiting
Age: 18Years - 65Years
All Genders
ID07170449
Investigation of the Relationship Between Ultrasonographic Parameters and Tactile Sensation in Carpal Tunnel Syndrome
Led by Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Updated on 2025-09-12
84
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how different ultrasound measurements relate to the level of tactile sensation in patients with carpal tunnel syndrome (CTS), a common nerve compression condition. The study focuses on patients with mild to moderate CTS diagnosed through electrodiagnostic tests. It aims to understand how ultrasound parameters used in diagnosis connect to sensory complaints, such as numbness and sensory loss, which affect daily hand use. The study involves diagnostic tests including nerve conduction studies that measure sensory and motor responses in the upper limbs, median nerve ultrasound to assess nerve size and characteristics, and tactile sensory tests to evaluate sensory function. These assessments will help explore the relationship between ultrasound findings and the level of sensory disturbance in patients with CTS. Participants will undergo various evaluations over three months, including ultrasound scans of the median nerve and sensory tests like two-point discrimination and the Semmes Weinstein test. Questionnaires on symptom severity and quality of life will also be completed. The research team will monitor these outcomes to better understand sensory changes in CTS and their association with ultrasound measures.
CONDITIONS
Brief Title
Investigation of the Relationship Between Ultrasonographic Parameters and Tactile Sensation in Carpal Tunnel Syndrome
Who Can Participate
Age: 18Years - 65Years
All Genders
Eligibility Criteria
You may qualify if you...
- Electrodiagnostic diagnosis of carpal tunnel syndrome with pain, numbness, burning, and tingling consistent with the median nerve dermatomal area lasting at least 6 weeks
- Literate
- Agree to participate in the study
- Age between 18 and 65 years
You will not qualify if you...
- Concomitant diabetes, systemic inflammatory disease, active infection, or history of malignancy
- Younger than 18 or older than 65 years
- Illiteracy
- Refusal to participate in the study
- Diseases with neuropathic pain such as polyneuropathy, radiculopathy, or multiple sclerosis
- Other upper extremity entrapment neuropathies like cubital tunnel syndrome
- Previous surgery for carpal tunnel syndrome
- Rheumatoid arthritis or advanced hand osteoarthritis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Up to 3 months
Participants undergo nerve conduction studies, median nerve ultrasonography, and sensory testing to assess carpal tunnel syndrome.
Assessments at baseline and at 3 months
Long-term Monitoring
Duration - Up to 3 months
Participants are monitored to observe the relationship between sonographic measurements and tactile sensation over time.
Follow-up assessments at 3 months
Trial Site Locations
Total: 1 location
1
Sultan Abdülhamit Han Trainin and Educational Hospital
Üsküdar, İ̇stanbul, Turkey (Türkiye)
Actively Recruiting
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Research Team
M
Müyesser Cavlak, PhD
F
Feyza Nur Yücel, Specialist
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Assessment of symptom severity and functional status in patients with carpal tunnel syndrome: reliability and functionality of the Turkish version of the Boston Questionnaire.
Melek Sezgin, Nurgül Arinci Incel, Sevim Serhan...
https://pubmed.ncbi.nlm.nih.gov/17083175Structural validity of the Boston Carpal Tunnel Questionnaire and its short version, the 6-Item CTS symptoms scale: a Rasch analysis one year after surgery.
Juhani Multanen, Jari Ylinen, Teemu Karjalainen...
https://pubmed.ncbi.nlm.nih.gov/32919457AAEE minimonograph #26: The electrodiagnosis of carpal tunnel syndrome.
J C Stevens
https://pubmed.ncbi.nlm.nih.gov/3821791Nerve echogenicity and intranerve CSA variability in high-resolution nerve ultrasound (HRUS) in chronic inflammatory demyelinating polyneuropathy (CIDP).
Anna Lena Fisse, Kalliopi Pitarokoili, Jeremias Motte...
https://pubmed.ncbi.nlm.nih.gov/30554264Reliability of two-point discrimination test in carpal tunnel syndrome patients.
Tomasz Wolny, Paweł Linek
https://pubmed.ncbi.nlm.nih.gov/29482409Correlating ultrasound findings of carpal tunnel syndrome with nerve conduction studies.
Jae Min Kim, Min Wook Kim, Young Jin Ko
https://pubmed.ncbi.nlm.nih.gov/23512486Pathophysiology of carpal tunnel syndrome.
Moutasem S Aboonq
https://pubmed.ncbi.nlm.nih.gov/25630774Factors affecting symptoms and functionality of patients with carpal tunnel syndrome: a retrospective study.
Hulya Yucel
https://pubmed.ncbi.nlm.nih.gov/25995565