Investigation on Hyperalgesia After Thoracoscopic Lung Cancer Surgery and Effects of Flurbiprofen Axidate Combined with Noise-Cancelling Headphones Music

What this Trial Is About

Researchers are investigating hyperalgesia, or increased sensitivity to pain, in patients undergoing thoracoscopic radical lung cancer surgery. This study aims to understand the current state and factors influencing hyperalgesia after surgery, and to evaluate how combining the drug flurbiprofen axidate with noise-cancelling earphone music during surgery may affect postoperative pain levels. The study randomly assigns patients to one of three groups: flurbiprofen axidate combined with noise-cancelling headphones playing music, flurbiprofen axidate combined with noise-cancelling headphones without music, or flurbiprofen axidate alone via drip. The drug is given 30 minutes before anesthesia, and in the headphone groups, noise-cancelling headphones are applied after anesthesia induction and worn throughout the surgery. Participants will be assessed before surgery and on the first and second days after surgery for mechanical pain threshold on the healthy arm and surgical area. Pain levels are measured using a numerical rating scale, and use of additional analgesics and patient-controlled analgesia pumps are tracked within two days after surgery. Researchers also monitor intraoperative medication use and adverse reactions like nausea or hypotension. The total duration of participation spans surgery day and two days post-surgery for outcome evaluation.

Investigation on the Status Quo of Hyperalgesia in Patients After Thoracoscopic Operation and Study on the Effect of Intraoperative Intervention