Reliability and validity of the modified Toronto Clinical Neuropathy Score in diabetic sensorimotor polyneuropathy.
V Bril, S Tomioka, R A Buchanan...
https://pubmed.ncbi.nlm.nih.gov/19317818Actively Recruiting
Led by Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Updated on 2025-09-12
86
Participants Needed
2
Research Sites
11 weeks
Total Duration
Researchers are investigating how ultrasonographic measurements of the lower extremity nerves relate to walking ability and balance in adults with type 2 diabetes who have peripheral polyneuropathy. This study aims to understand how these nerve changes impact daily life, physical activity, gait, and balance. Diabetic neuropathy is a common complication that affects nerve function and quality of life, and early detection using ultrasonography could improve patient care. The study involves two groups: healthy volunteers and patients with diabetic peripheral polyneuropathy. Participants will undergo ultrasonographic nerve assessments using a specialized ultrasound device. Additional evaluations include balance testing with the Biodex Balance System, neuropathic pain scales, physical performance tests such as the six-minute walk test and Timed Up and Go Test, as well as quality of life and physical activity questionnaires. All measurements and tests will occur once during the study period. Participants will have a single evaluation session where demographic and clinical data are collected, including blood tests and neuropathy assessments. The study measures include ultrasonography, balance, pain scales, nerve function scores, walking tests, and quality of life surveys. The research will analyze these outcomes to better understand nerve changes and their effects on balance and gait in diabetic polyneuropathy. The study is planned between December 2024 and May 2025 with a total of 86 participants.
CONDITIONS
Investigation of Ultrasonographic Measurements of Lower Extremity Nerves in Type 2 Diabetes Patients With Peripheral Polyneuropathy
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a comprehensive assessment including ultrasonography of lower extremity nerves, balance and gait performance tests, pain and neuropathy scales, physical examination, and functional capacity tests to evaluate diabetic peripheral polyneuropathy and overall nerve function.
1 visit (in-person)
Total: 2 locations
1
Sultan 2. Abdulhamid Han Training and Research Hospital
Istanbul, Üsküdar, Turkey (Türkiye), 34674
Active, Not Recruiting
2
Sultan 2. Abdulhamid Han Training and Research Hospital
Istanbul, Üsküdar, Turkey (Türkiye)
Actively Recruiting
S
Semiha Özgüç
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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