Actively Recruiting

Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06778005

Investigation of Ultrasonographic Measurements of Lower Extremity Nerves in Type 2 Diabetes Patients With Peripheral Polyneuropathy

Led by Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Updated on 2025-09-12

86

Participants Needed

2

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to quantitatively evaluate ultrasonographic measurements of the lower extremity nerves in patients diagnosed with diabetic polyneuropathy and to investigate the relationship with gait, static and dynamic balance performance. In this study, we aimed to investigate the effect of ultrasonographic findings of lower extremity nerves on quality of daily life, physical activity, gait and balance in patients with diabetic peripheral polyneuropathy.

CONDITIONS

Official Title

Investigation of Ultrasonographic Measurements of Lower Extremity Nerves in Type 2 Diabetes Patients With Peripheral Polyneuropathy

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Ability to read and write
  • Signed voluntary consent form
  • For diabetic group: Diagnosed with type 2 diabetes based on standard criteria
  • Diagnosed with diabetic peripheral polyneuropathy through EMG evaluation (for diabetic group)
Not Eligible

You will not qualify if you...

  • Under 18 years or over 65 years of age
  • Diagnosed with type 1 diabetes
  • Use of medications that cause polyneuropathy
  • Other causes of neuropathic pain such as lumbar radiculopathy, spinal stenosis, hereditary, inflammatory, or entrapment neuropathies
  • Underwent lower extremity surgery (spine, hip, knee, foot) in the last 6 months
  • Peripheral artery disease
  • Vitamin B12 deficiency
  • Active foot ulcer
  • History of lower extremity amputation
  • Severe cardiopulmonary insufficiency (stage 3-4)
  • Myocardial infarction within the last month
  • History of unstable angina
  • Active systemic inflammatory diseases or active cancer
  • Vestibular disorders
  • Cognitive impairment
  • Osteoarthritis in the lower extremity
  • Pregnancy
  • Body Mass Index of 30 or higher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Sultan 2. Abdulhamid Han Training and Research Hospital

Istanbul, Üsküdar, Turkey (Türkiye), 34674

Active, Not Recruiting

2

Sultan 2. Abdulhamid Han Training and Research Hospital

Istanbul, Üsküdar, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Semiha Özgüç

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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