Actively Recruiting
An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors
Led by Mayo Clinic · Updated on 2026-04-28
47
Participants Needed
1
Research Sites
114 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
F
Food and Drug Administration (FDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This phase II trial studies how well the addition of 18F-DOPA (amino acid) positron emission tomography (PET)/computed tomography (CT) to standard of care (SOC) imaging can improve the clinical management of patients with brain tumors in over 50% of cases. PET is an imaging test that helps to measure the information about functions of tissues and organs within the body. A PET scan uses a radioactive drug (radiotracer) to show this activity. CT scan uses X-rays to create images of the bones and internal organs within the body. Combining a PET scan with a CT scan can help make the images easier to interpret. PET/CT scans are hybrid scanners that combine both of the two modalities into a single scan. This allows images of both anatomy (CT) and function (PET) to be taken during the same scan. The 18F-DOPA PET/CT scan is done with a very small amount of a radioactive tracer called FDOPA. The PET/CT scan is then used to detect the location of tumors. Using the 18FDOPA-PET/CT scan in addition to the SOC scan may improve the clinical management of patients with brain tumors.
CONDITIONS
Official Title
An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 and older
- Diagnosis of a brain tumor
- Medical indication for amino acid PET imaging such as presurgical evaluation, radiation planning, unclear MRI results, or need for enhanced monitoring
- Ability to provide consent or have a representative provide consent
You will not qualify if you...
- Unable to undergo PET imaging
- Pregnant or nursing persons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
C
Clinical Trials Referral Office
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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