Actively Recruiting
An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer
Led by Jonsson Comprehensive Cancer Center · Updated on 2025-11-10
60
Participants Needed
1
Research Sites
245 weeks
Total Duration
On this page
Sponsors
J
Jonsson Comprehensive Cancer Center
Lead Sponsor
L
LUNGevity Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The phase I/II trial assess the safety and efficacy of a new positron emission tomography (PET) test for early diagnosis of lung cancer. This study uses PET and Me-4FDG new glucose tracer (alpha-methyl-4-deoxy-4-\[(18)F\]fluoro-D-glucopyranoside) designed specifically to determine glucose update into cells in the body. PET is a non-invasive imaging method used to detect cancer in patient. Me4FDG is a radioactive glucose tracer used in PET to locate cells in the body taking up glucose by SGLT2. SLGT2 is a sodium glucose transport protein that accumulates glucose in some cells, e.g. kidney cells and tumors. This study may help researcher determine how effective PET with ME4FDG tracer works in detecting lung cancer.
CONDITIONS
Official Title
An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Lung nodule ≥ 1 cm seen on CT imaging
- For cancer group: Pathologically confirmed lung adenocarcinoma by surgical specimen or needle biopsy
- For benign group: Lung nodules considered clinically benign based on Fleischner Society Guidelines and lung-RADS score 1-3
You will not qualify if you...
- Pregnancy
- Diagnosis of diabetes
- Current treatment with SGLT2 inhibitors or metformin
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Yesenia Calzada
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
Y
Yesenia Calzada
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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