Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06826066

Involvement of the Immune System in Intrinsic Radiosensitivity

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-01-15

40

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Radiotherapy is one of the major treatments for cancer. It may be indicated in more than two-thirds of patients, regardless of cancer location or disease stage. The mechanisms of radiotherapy action are numerous: halting tumor proliferation, inducing tumor cell death, triggering anti-tumor immune responses, and ensuring both local and systemic tumor control. As a result, current treatments are highly effective, providing, for instance, a 5-year overall survival rate of about 90%-95% for localized breast and prostate cancers.

CONDITIONS

Official Title

Involvement of the Immune System in Intrinsic Radiosensitivity

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 880 18 years
  • Patients who have been treated with radiotherapy
  • Absence of toxicity grade 2 or higher
  • Patients without psychiatric, sociological, family, or geographical difficulties that could interfere with patient compliance to the protocol or follow-up
  • Information and signed informed consent
  • Affiliated with social security
Not Eligible

You will not qualify if you...

  • Inability to obtain patient consent
  • Patient refusing blood sample collection
  • Patient deprived of liberty or under legal protection (under guardianship, under curatorship)
  • Patients who have experienced radiation-induced toxicity of grade 2 or higher
  • Disease progression, relapse
  • Patient under State Medical Aid

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpital Henri Mondor, 1 rue Gustave Eiffel,

Créteil, Île-de-France Region, France, 94000

Actively Recruiting

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Research Team

B

BELKACIMI Mr Yazid, PhD

CONTACT

D

DEBBI Mr Kamel, Dr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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