Actively Recruiting

Age: 50Years - 120Years
All Genders
NCT05892952

IONA Longitudinal Cohort Study

Led by Brain Health Scotland Life Sciences Ltd · Updated on 2025-09-19

10000

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Understanding more about how diseases that cause dementia develop is critical as the number of people living with, or affected by, dementia in Scotland continues to grow. The IONA Longitudinal Cohort Study (LCS) has been set up to gather information about people's cognitive health (their memory and thinking abilities), their lifestyle and health risk factors for future dementia (such as hearing loss and obesity), genetics and disease biomarkers, over a number of years. The IONA LCS has three main objectives: Firstly to develop this cohort that is well characterised (also known as being "well-phenotyped") that represent the Scottish population (taking into consideration age, sex, ethnicity and education). The second objective is to use this data to build disease models to better understand trajectories of diseases, and identify any sub-populations who have different (i.e. better, worse) disease trajectories. Finally the third objective for IONA LCS is to offer people an optional consent to hear about future studies they may be interested in taking part in.

CONDITIONS

Official Title

IONA Longitudinal Cohort Study

Who Can Participate

Age: 50Years - 120Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age at least 50 years.
  • Living in Scotland.
  • Able to read and write and with minimum 7 years of formal education.
  • Have a study partner who is aged 18 years or older.
  • Have capacity to provide informed consent at baseline.
  • Able to speak English to a level where the cognitive assessments can be completed.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Scottish Brain Sciences Arran Facility

Edinburgh, Lothian, United Kingdom, EH12 9DQ

Actively Recruiting

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Research Team

S

Sarah Gregory, PhD

CONTACT

J

Joseph Milne

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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