Actively Recruiting
The ISAR InflEx Trial (Inflammation and Exercise)
Led by Department of Cardiology German Heart Center Munich TUM University Hospital · Updated on 2026-04-24
33
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
Sponsors
D
Department of Cardiology German Heart Center Munich TUM University Hospital
Lead Sponsor
T
The German Heart Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD). This study aims to systematically characterize and compare the effects of three distinct exercise modalities - moderate-intensity, vigorous-intensity, and short-duration maximal exercise - each differing in duration and intensity, on systemic inflammation and immune function. The study investigates the potential of exercise as an effective anti-inflammatory intervention for the prevention of CVD.
CONDITIONS
Official Title
The ISAR InflEx Trial (Inflammation and Exercise)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- BMI between 25.0 and 30.0 kg/m²
- Age between 18 and 45 years
- Provided informed consent
- No regular physical activity (1 or fewer structured exercise sessions per week)
- Willingness to strictly follow and adhere to the intervention protocol throughout the study
You will not qualify if you...
- Presence of any acute or chronic illness
- Pregnancy or breastfeeding
- Active smoking
- Regular use of medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
German Heart Centre
München, Bavaria, Germany, 80636
Actively Recruiting
Research Team
H
Hendrik B Sager, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
3
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