Actively Recruiting
Led by Chuncheon Sacred Heart Hospital · Updated on 2025-05-29
100
Participants Needed
2
Research Sites
N/A
Total Duration
Researchers are evaluating pain control methods in patients undergoing arthroscopic rotator cuff repair. This randomized, double-blind trial compares the effects of an interscalene brachial plexus block combined with suprascapular and axillary nerve blocks using ropivacaine versus the same brachial plexus block combined with placebo (saline) nerve blocks. The study aims to assess differences in pain levels and patient satisfaction at various times before and after surgery, as well as changes in blood markers related to stress and inflammation. Participants receive an ultrasound-guided interscalene brachial plexus block with ropivacaine immediately before surgery. They are then assigned to receive either suprascapular and axillary nerve blocks with ropivacaine or placebo blocks with saline. Both groups use low fixed dose patient-controlled analgesia with fentanyl and nefopam during the postoperative period. The study measures outcomes at multiple timepoints from before surgery up to 48 hours after. During the study, participants' pain scores and satisfaction are recorded preoperatively and at 1, 3, 6, 12, 18, 24, 36, and 48 hours after surgery. Blood samples are collected before surgery and at 1, 6, 12, 24, and 48 hours postoperatively to analyze levels of cortisol, various interleukins, substance P, serotonin, beta-endorphin, and norepinephrine. This detailed monitoring helps researchers understand the effects of the nerve blocks on pain and biological stress responses following rotator cuff repair.
CONDITIONS
ISB With SSNB & ANB
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - 48 hours
Participants undergo arthroscopic rotator cuff repair surgery with preemptive regional nerve blocks and receive patient-controlled analgesia at a low fixed dose for pain control.
1 baseline visit (surgery day) and multiple assessments during 48 hours postoperatively
Duration - 48 hours
Participants are monitored for pain levels, satisfaction, and blood markers through 48 hours after surgery to assess the effects of the nerve blocks and analgesia.
Several visits or assessments at postoperative 1, 3, 6, 12, 18, 24, 36, and 48 hours
Total: 2 locations
1
Hallym University Chuncheon Sacred Heart Hospital
Chuncheon, Gangwon-do, South Korea, 24253
Not Yet Recruiting
2
Hallym University Chuncheon Sacred Heart Hospital
Chuncheon, Gangwon-do, South Korea, 24253
Actively Recruiting
J
Jung-Taek Hwang, MD, PhD
S
Su-Jung Seo, PhD
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Jae Jun Lee, Do-Young Kim, Jung-Taek Hwang...
https://pubmed.ncbi.nlm.nih.gov/24880194Jae Jun Lee, Do-Young Kim, Jung-Taek Hwang...
https://pubmed.ncbi.nlm.nih.gov/32975624