Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT03481205

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

Led by Enrique Leira · Updated on 2025-11-10

10

Participants Needed

1

Research Sites

343 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.

CONDITIONS

Official Title

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 80 years
  • Suspected acute ischemic stroke with symptoms suggesting large vessel occlusion such as aphasia, agnosia, neglect, visual field cut, or gaze preference
  • Patient screened for rtPA and received rtPA if eligible
  • Subject or legally authorized representative able to give consent at assessment
  • NIH Stroke Scale score between 6 and 20
Not Eligible

You will not qualify if you...

  • Any intracranial hemorrhage seen on CT scan at community hospital
  • History of ischemia or blood vessel problems in arms or legs that prevent blood pressure cuff use, including stenosis, subclavian steal syndrome, soft tissue, orthopedic or vascular injury, or mastectomy
  • History of diabetes mellitus
  • Participation in another clinical trial
  • Patient is incarcerated
  • Pregnancy; patients aged 18-55 must have a negative pregnancy test
  • Unsafe agitation for ischemic preconditioning
  • Presence of arteriovenous fistula in upper limb

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Iowa

Iowa City, Iowa, United States, 52242

Actively Recruiting

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Research Team

A

Amir Shaban, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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Ischemic Conditioning During Air tRansport Save penUmbral Tissue | DecenTrialz