Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
NCT07003113

Ischemic Preconditioning in Osteoarthritis and Back Pain

Led by University of Illinois at Chicago · Updated on 2025-11-17

24

Participants Needed

1

Research Sites

67 weeks

Total Duration

On this page

Sponsors

U

University of Illinois at Chicago

Lead Sponsor

N

National Institute on Disability, Independent Living, and Rehabilitation Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

CONDITIONS

Official Title

Ischemic Preconditioning in Osteoarthritis and Back Pain

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Reported knee pain using American College of Rheumatology (ACR) criteria
  • Reported back pain with Oswestry Disability Index (ODI) score greater than 12
  • Ability to walk for at least 3 minutes without the use of walking aids
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Younger than 50 years old
  • History of knee or hip replacements
  • History of steroid injection within the previous 6 months
  • Presence of neuromuscular joint condition affecting lower extremity function
  • History of blood clots in the leg or any condition where thigh compression is not allowed
  • History of heart failure or thrombosis
  • Allergy to ultrasound gel
  • History of spine surgery
  • Non-English speaker
  • Currently pregnant or planning pregnancy during the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Human and Sport Performance Lab

Chicago, Illinois, United States, 60608

Actively Recruiting

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Research Team

S

Shraddha Sudhir

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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