Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
ID05887440

Effects of Isokinetic Strength Training of Knee Flexor and Extensor Muscles on Walking in Hemiparetic Patients With Knee Extension Thrust

Led by Rennes University Hospital · Updated on 2023-09-05

12

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of isokinetic strength training on walking performance in hemiparetic patients who experience knee extension thrust during walking. This study focuses on patients who have had a hemorrhagic or ischemic stroke, either in the subacute stage (less than 6 months) or chronic stage (more than 6 months). The study uses a single case experimental design with multiple baselines to test the impact of the intervention with a small group of 12 patients. Participants will continue their usual rehabilitation program at a day hospital, which includes physiotherapy, physical activity, and if needed, occupational and speech therapy. After a randomized baseline period of 3, 4, or 5 weeks, isokinetic strength training will be added to the rehabilitation. The training involves three sessions per week over five weeks, focusing on eccentric and concentric contractions of the knee flexor and extensor muscles at specific speeds and intensities. During the study, researchers will measure spontaneous walking speed and various walking and strength assessments over 25 weeks. These include tests such as extensor thrust analysis, walking speed, stair climbing, inclined plane, six-minute walk, sit-to-stand, fatigue, and strength evaluations. Participants will be monitored through repeated assessments, and their progress will be analyzed using specific statistics and visual methods to understand the training's impact.

CONDITIONS

Brief Title

Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hemiparetic patient due to hemorrhagic or ischemic stroke
  • Subacute stroke stage (less than 6 months) or chronic stroke stage (more than 6 months), with 6 patients in each group
  • Age between 18 and 75 years
  • Able to walk 10 meters independently without any assistive devices
  • Presence of knee extension thrust during the stance phase of the gait cycle
  • Scheduled for a rehabilitation program including isokinetic strength training
  • Affiliated to social security
  • Provided and signed informed consent
Not Eligible

You will not qualify if you...

  • Major comprehension deficit preventing informed consent or participation in strength training
  • Unstable cardiovascular condition
  • Musculoskeletal disorders causing knee pain that prevent strength training
  • Botulinum toxin injection in lower limb within past 3 months or repeated injections
  • Proprioception trouble as assessed by Fugl-Meyer Assessment
  • Spasticity of triceps surae muscle rated 2 or higher on Modified Ashworth scale
  • Ankle dorsiflexion angle less than 90 degrees
  • Pregnant or breastfeeding women
  • Persons under safety measures

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Baseline Rehabilitation Program

Duration - 3 to 5 weeks depending on randomization

Participants undergo a conventional rehabilitation program including physiotherapy and physical activity 4 days per week in a day hospital setting. Occupational and speech therapy are provided if necessary.

4 days per week for up to 5 weeks

Isokinetic Strength Training Treatment

Duration - 5 weeks

Participants receive an isokinetic strength training program added to their rehabilitation, involving 3 sessions per week for 5 weeks focusing on knee flexor and extensor muscles with specific contraction exercises.

3 sessions per week for 5 weeks

Follow-up Assessments

Duration - Up to 25 weeks

Participants are assessed for walking speed, extensor thrust analysis, strength, fatigue, and other functional tests over a 25-week period after treatment.

Visits scheduled according to assessment timetable

Trial Site Locations

Total: 1 location

1

CHU de Rennes

Rennes, France, 35033

Actively Recruiting

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Research Team

S

Sophie HAMEAU, PhD

K

Krsitell COAT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

3

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