Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06820125

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation

Led by Universita di Verona · Updated on 2025-02-11

48

Participants Needed

1

Research Sites

156 weeks

Total Duration

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AI-Summary

What this Trial Is About

The first aim of this project is to investigate the effects of different high-tech neurorehabilitation interventions (cognitive, motor, and combined cognitive-motor) on both cognitive and motor disability outcomes in people with multiple sclerosis (MS). The second aim is to identify the cognitive and motor profiles of MS patients who benefit the most from either the combined cognitive-motor rehabilitation intervention or the isolated cognitive or motor treatments.

CONDITIONS

Official Title

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of mild or severe cognitive impairment based on neuropsychological tests below the cut-off score (5th percentile)
  • Mild to moderate walking disability with Expanded Disability Status Scale (EDSS) between 3 and 6
  • No relapse or steroid use in the past three months
  • Adequate visual and auditory capacity to operate computer software
Not Eligible

You will not qualify if you...

  • Presence of neurological disorders other than multiple sclerosis
  • Major psychiatric disorders
  • High levels of anxiety and/or depression (scores above threshold on Italian adaptation of DASS-21)
  • Substance abuse
  • Any rehabilitation intervention in the month before recruitment
  • Unstable or changed pharmacological therapy during the study
  • Presence of paroxysmal vertigo
  • Lower limb botulinum toxin injections within the previous 12 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sezione medicina fisica e riabilitativa dipartimento di neuroscienze

Verona, verona, Italy, 37134

Actively Recruiting

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Research Team

V

Valentina Varalta

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation | DecenTrialz