Actively Recruiting

Phase 1
Age: 18Years - 60Years
All Genders
NCT06485505

Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis

Led by Zagazig University · Updated on 2026-04-23

36

Participants Needed

1

Research Sites

124 weeks

Total Duration

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AI-Summary

What this Trial Is About

3 groups of patients with onychomycosis will be recruited. Group A will receive itraconazole alone. Group B will receive itraconazole + low dose isotretinoin and group C will be treated with itraconazole + excimer light sessions.

CONDITIONS

Official Title

Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of dermatophyte onychomycosis confirmed by KOH examination and fungal culture
  • At least 1 month washout from any previous onychomycosis therapy
  • Age between 18 and 60 years
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Active infection or inflammation in or around nails other than onychomycosis
  • Liver disease
  • Heart disease
  • Diabetes mellitus
  • Current use of statin therapy or photosensitizing drugs

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zagazig University Hospitals

Zagazig, Zagazig, Egypt, 44519

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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