Actively Recruiting

Age: 12Years - 99Years
All Genders
NCT06376786

Italian iTTP Registry

Led by Fondazione Luigi Villa · Updated on 2024-07-10

132

Participants Needed

1

Research Sites

310 weeks

Total Duration

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AI-Summary

What this Trial Is About

ItaliTTP is an observational, prospective, single-arm, national, multicenter, non-pharmacological cohort study aimed at better defining and understanding the natural history, disease severity, and clinical outcomes of patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) in Italy. A minimum of 132 consecutive patients with acute iTTP (first event or relapse) will be enrolled for 3 years, with the possibility of extension, with a follow-up period of 3 years.

CONDITIONS

Official Title

Italian iTTP Registry

Who Can Participate

Age: 12Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with an acute iTTP episode (first event or relapse), defined by thrombocytopenia and microangiopathic hemolytic anemia, with severe deficiency of ADAMTS13 activity (< 10 IU/dL or <10% of normal) and anti-ADAMTS13 autoantibodies
  • Both male and female patients aged 12 years or older
  • Patients who have signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Patients who have not signed informed consent to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, MI, Italy, 20122

Actively Recruiting

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Research Team

S

Sandra Maccarone

CONTACT

I

Ilaria Mancini, MSc, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Italian iTTP Registry | DecenTrialz