Actively Recruiting

Age: 18Years +
All Genders
NCT06339255

Italian Observational Study on CAR-T Therapy for Lymphoma

Led by Paolo Corradini · Updated on 2024-04-01

5300

Participants Needed

1

Research Sites

530 weeks

Total Duration

On this page

Sponsors

P

Paolo Corradini

Lead Sponsor

A

Annalisa Chiappella

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study on chimeric antigen receptor T-cell therapy is to monitor the feasibility, efficacy, toxicity and biomarkers in a real life setting. Partecipants will be asked to agree to their clinical data collection and to partecipate to the optional biological study that aims to evaluate biomarkers of toxicity and response (clinical characteristics, cytokine profile, cellcomposition and type of the CAR-T cell product, lymphoma genomics). The study will evaluate even the disease response according to lugano criteria by PET and CT in routine clinical activity.

CONDITIONS

Official Title

Italian Observational Study on CAR-T Therapy for Lymphoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with diagnosis of DLCBL, PMBCL, MCL and FL eligible for CAR-T treatment with commercially available products in Italy.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Fondazione IRCCS Istituto Nazionale Tumori

Milan, Italy, 20133

Actively Recruiting

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Research Team

P

Paolo Corradini, Professor

CONTACT

A

Anisa Bermema, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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