Actively Recruiting
iTBS for Acute Ischemic Stroke After Thrombectomy
Led by Yi Yang · Updated on 2025-04-30
178
Participants Needed
1
Research Sites
66 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized, single-blind, parallel-controlled clinical trial is to evaluate the efficacy and safety of intermittent theta burst stimulation (iTBS) as an adjunctive therapy for acute anterior circulation ischemic stroke patients who have undergone successful mechanical thrombectomy (MT). The study population includes adults aged 18-85 with NIHSS scores 5-25 post-MT and eTICI≥2b reperfusion.
CONDITIONS
Official Title
iTBS for Acute Ischemic Stroke After Thrombectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 85 years, any gender
- Acute ischemic stroke due to blockage in the anterior circulation large vessels confirmed by CTA or DSA
- Mechanical thrombectomy performed within 24 hours of symptom onset
- Successful reperfusion after thrombectomy with an eTICI score of 2b or higher
- NIHSS score between 5 and 25 at 24 hours post-thrombectomy, with at least 2 points in one limb
You will not qualify if you...
- Pre-stroke modified Rankin Scale score of 2 or higher
- PH2-type intracranial hemorrhage detected on brain CT after thrombectomy
- Intracranial stent placement during mechanical thrombectomy
- Contraindications to iTBS such as history of epilepsy or seizures, implanted pacemaker, cochlear implant, or other electronic/magnetic-sensitive devices
- Severe consciousness impairment, cognitive dysfunction, or psychiatric disorders preventing compliance with treatment
- Expected survival less than 3 months or inability to complete follow-up
- Participation in another interventional study
- Any other condition considered unsuitable for enrollment by the investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
Y
Yi Yang, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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