Actively Recruiting
Quality of Recovery After Video-assisted Thoracoscopic Surgery Comparing Single and Three Level Intertransverse Process Block
Led by Chinese University of Hong Kong · Updated on 2025-04-11
80
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating recovery quality after video-assisted thoracoscopic surgery (VATS) in patients with primary lung carcinoma. The study compares two methods of intertransverse process block (ITPB)—a single-level injection versus three-level injections—to assess their effectiveness in pain control and quality of recovery, measured by the QoR15 score at 24 hours after surgery. The study aims to improve pain management while reducing risks associated with traditional regional anesthesia techniques. Participants receive either a single-level ITPB at the T5 vertebral level combined with two sham saline injections at T3 and T7, or a three-level ITPB with injections at T3, T5, and T7. The blocks are performed under ultrasound guidance with local anesthetic injected near the retro-superior costotransverse ligament (retro-SCTL) space. This approach aims to block somatic and sympathetic nerve signals to reduce postoperative pain while avoiding risks like pleural puncture. During the study, participants will be monitored for quality of recovery 24 hours after surgery. Researchers will also assess pain levels at rest and during movement, sensory changes at 15 and 30 minutes after block completion, and medication use during and after surgery. The study includes careful safety monitoring and follow-up for up to 48 hours post-surgery to evaluate analgesic effectiveness and side effects.
CONDITIONS
Brief Title
ITPB 1 vs 3 in VATS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ASA physical status I to III patients
- Age between 18 and 80 years
- Patients with primary carcinoma lung scheduled for resection under VATS procedure
You will not qualify if you...
- Patient refusal
- Local skin infection at the area of injection
- Coagulopathy
- History of allergy to local anaesthetics
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo video-assisted thoracoscopic surgery (VATS) and receive either a single level or three level Intertransverse Process Block (ITPB) as a regional anesthetic technique to manage pain during surgery.
1 surgical visit (in-person)
Duration - 48 hours post surgery
Participants are monitored for quality of recovery and pain management after surgery, including assessment of analgesic efficacy and side effects.
Visits at 15 minutes, 30 minutes, 24 hours, and 48 hours after surgery
Trial Site Locations
Total: 1 location
1
Department of Anaesthesia, Pain and Perioperative Medicine, Prince of Wales Hospital, Shatin
New Territories, Hong Kong
Actively Recruiting
Research Team
A
Ayla Wong, RN, BN
M
Manoj K Karmakar, MD, FRCA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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