Actively Recruiting
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
Led by Pedro Morgado · Updated on 2025-01-27
120
Participants Needed
1
Research Sites
134 weeks
Total Duration
On this page
Sponsors
P
Pedro Morgado
Lead Sponsor
H
Hospital de Braga
Collaborating Sponsor
AI-Summary
What this Trial Is About
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes related and on the neurobiological underpinnings of emotion regulation (ER). After a baseline assessment, the investigators will implement an internet-based cognitive behavioral therapy (iCBT) protocol and assess its efficacy on the modulation of ER and OCD severity. Specifically, the investigators will (1) examine to what extent the iCBT intervention modulates ER and the associated neurobiological mechanisms and (2) identify candidate biomarkers of successful treatment response.
CONDITIONS
Official Title
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Primary diagnosis of current OCD according to the fifth Diagnostic and Statistical Manual of Mental Disorders
- Yale-Brown Obsessive Compulsive Scale (YBOCS) score of 16 or higher
- Stable psychotropic medication for at least 2 months before the study and maintained during the study
- Access to internet and a computer or tablet to participate in the online intervention
You will not qualify if you...
- Contraindications to MRI
- History of neurological disorders or traumatic brain injury
- Received cognitive behavioral therapy (CBT) for OCD in the past 2 years
- Currently undergoing any psychological treatment
- Suicidal thoughts
- Current alcohol or drug abuse
AI-Screening
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Trial Site Locations
Total: 1 location
1
Life and Health Sciences Research Institute, School of Medicine, University of Minho
Braga, Gualtar, Portugal, 4710-057
Actively Recruiting
Research Team
P
Pedro Morgado, M.D, Ph.D.
CONTACT
M
Mafalda Sousa, M., Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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