Actively Recruiting
Evaluation of Intravenous Magnesium Administration in the Treatment of Dysmenorrhea
Led by Havva Betül Bacak · Updated on 2025-11-25
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial investigates the pain relief effects of intravenous magnesium sulfate in women aged 18 to 35 years who come to the emergency department with acute primary dysmenorrhea. The study compares magnesium sulfate to dexketoprofen, a standard nonsteroidal anti-inflammatory drug, to see which provides better pain control. Participants have regular menstrual cycles and experience significant pain, as measured by a pain scale. Participants are randomly assigned to receive either 2 ampoules of magnesium sulfate or 50 mg of dexketoprofen, both diluted in 100 ml of normal saline and given intravenously over 15 minutes. Pain levels will be measured before treatment and one hour after administration using the Visual Analog Scale (VAS). The study also monitors patient satisfaction, vital signs, and possible side effects. During the study, participants will be assessed at admission and one hour after treatment to evaluate changes in pain intensity. Researchers will track vital signs and any adverse events. The total participation involves these assessments in the emergency setting, focusing on the immediate response to treatment for acute dysmenorrhea.
CONDITIONS
Brief Title
IV Magnesium in the Treatment of Acute Dysmenorrhea
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18 to 35 years
- Presenting with a diagnosis of primary dysmenorrhea
- Having regular menstrual cycles within the last 6 months
- Having a Visual Analog Scale (VAS) pain score of 6 or higher at emergency admission
- Providing written informed consent for participation
You will not qualify if you...
- Secondary dysmenorrhea or underlying gynecological pathology
- Pregnancy or breastfeeding
- Use of analgesics or muscle relaxants within the last 3 days
- Known allergy to magnesium sulfate or dexketoprofen trometamol
- History of renal failure, cardiac arrhythmia, or serious systemic disease
- Inability to assess pain due to mental disability or communication disorder
- Failure to provide informed consent for participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) at emergency admission for eligibility assessment and baseline pain measurement
Duration - Single treatment session
Participants receive an intravenous infusion of either magnesium sulfate or dexketoprofen to manage acute dysmenorrhea pain.
1 visit (in-person) for intravenous administration lasting approximately 15 minutes and pain assessment before and 1 hour after treatment
Trial Site Locations
Total: 1 location
1
SBÜ Gaziosmanpaşa Training and Research Hospital
Gaziosmanpaşa, Outside of the US, Turkey (Türkiye), 33400
Actively Recruiting
Research Team
E
ecenur çelikoğlu, md
Y
yağmur acıyiyen, md
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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