Actively Recruiting

Age: 12Years - 90Years
All Genders
NCT04208828

IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy

Led by University of Louisville · Updated on 2025-08-01

400

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serologic and/or endo organ abnormalities and findings consistent with autoimmune neuropathies, primarily involving the GI tract. These disorders have been known as autoimmune gastrointestinal neuropathies (GAIN) or also as autoimmune gastrointestinal dysmotility (AGID), among other terms. Some patients respond to intravenous immunoglobulin (IVIG) and this study, which is an observational clinical series, documents the patients, their findings and standardized responses to therapy with IVIG.

CONDITIONS

Official Title

IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy

Who Can Participate

Age: 12Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient with otherwise refractory symptoms of gastrointestinal (GI) motor disorders.
Not Eligible

You will not qualify if you...

  • Inability to receive intravenous immunoglobulin.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Louisville

Louisville, Kentucky, United States, 40202

Actively Recruiting

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Research Team

T

Thomas L Abell, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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