Actively Recruiting

Phase 1
Age: 18Years - 65Years
All Genders
NCT05584631

IVIG vs SCIG in CIDP

Led by Rutgers, The State University of New Jersey · Updated on 2025-12-11

20

Participants Needed

1

Research Sites

220 weeks

Total Duration

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AI-Summary

What this Trial Is About

Current dosing practices for immunoglobulin G (IgG) may be inadequate in extreme body weight. The current study will evaluate the influence of body composition on intravenous and subcutaneous administration of immunoglobulin G in patients.

CONDITIONS

Official Title

IVIG vs SCIG in CIDP

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged >18 years with a current diagnosis of CIDP based on European Federation of Neurological sciences / Peripheral Nerve Society diagnostic criteria
  • 1:1 conversion of IVIG to SCIG with weekly dose conversion within 0.2 to 0.4 mg/kg dose for SCIG
Not Eligible

You will not qualify if you...

  • Patients receiving IVIG for indications other than CIDP
  • Patients with liver impairment with liver enzymes greater than 3 times the upper limit of normal
  • Patients with reduced kidney function with creatinine clearance less than 50 mL/min
  • Active malignancies
  • Diabetes
  • Myasthenia gravis
  • Immunodeficiency
  • Autoimmune disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rutgers, The State University of New Jersey Clinical Research Center

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

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Research Team

L

Luigi Brunetti, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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