Actively Recruiting
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
Led by Samsung Medical Center · Updated on 2024-10-24
1400
Participants Needed
2
Research Sites
328 weeks
Total Duration
On this page
Sponsors
S
Samsung Medical Center
Lead Sponsor
C
Chonnam National University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of the study is to compare clinical outcomes between intravascular ultrasound (IVUS)-guided treatment decision versus fractional flow reserve (FFR)-guided treatment decision for non-infarct related artery stenosis in patients with acute myocardial infarction (AMI) and multivessel disease.
CONDITIONS
Official Title
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subject must be at least 19 years of age
- Acute ST-segment elevation myocardial infarction (STEMI), defined as ST-segment elevation ≥0.1 mV in ≥2 contiguous leads or new left bundle-branch block
- Acute non-ST-segment elevation myocardial infarction (NSTEMI), defined by elevated cardiac biomarkers plus symptoms or ECG/imaging evidence
- Successful primary percutaneous coronary intervention (PCI) within 12 hours of symptom onset for STEMI or within 72 hours for NSTEMI
- Multivessel disease with at least one stenosis >50% in a non-infarct related artery ≥2.25 mm by visual estimation
- Ability to understand risks, benefits, and alternatives and provide written informed consent
You will not qualify if you...
- Non-infarct related artery stenosis not suitable for PCI based on operator decision
- Cardiogenic shock (Killip class IV) at presentation or after infarct-related artery PCI
- Intolerance to Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Heparin, or Everolimus
- Known true anaphylaxis to contrast media
- Pregnancy or breastfeeding
- Non-cardiac conditions with life expectancy less than 2 years or likely protocol non-compliance
- Severe primary valvular heart disease including severe mitral or aortic regurgitation or stenosis
- Unwillingness or inability to follow study procedures
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Chonnam National University
Gwangju, South Korea
Not Yet Recruiting
2
Samsung Medical Center
Seoul, South Korea
Actively Recruiting
Research Team
J
Joo Myung Lee, MD, MPH, PhD
CONTACT
J
Joo-Yong Hahn, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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