Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
NCT05064540

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Led by Endologix · Updated on 2025-06-08

450

Participants Needed

29

Research Sites

492 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).

CONDITIONS

Official Title

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult age 21 and older
  • Subjects with minimum of 2 year life expectancy
  • Subjects have signed the informed consent document
  • Subjects with unruptured infrarenal AAA assessed eligible for endovascular repair with the trial devices
  • Patient must be able and willing to comply with all required follow-up exams
Not Eligible

You will not qualify if you...

  • Currently participating in another trial where the primary endpoint has not been reached yet
  • Known allergy to any of the device components
  • Pregnant (females of childbearing potential only)
  • Known connective tissue disorders
  • Known active infection
  • Subjects with pre-existing EVAR requiring repair or intervention
  • Medical, social, or psychological conditions that preclude receiving treatment or evaluations as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 29 locations

1

Huntsville Hospital

Huntsville, Alabama, United States, 35801

Active, Not Recruiting

2

University of Arizona

Tucson, Arizona, United States, 85716

Actively Recruiting

3

Washington Regional Medical Center

Fayetteville, Arkansas, United States, 72703

Actively Recruiting

4

Central Arkansas Veterans Healthcare System

Little Rock, Arkansas, United States, 72205

Actively Recruiting

5

The Regents of the University of California, San Diego

La Jolla, California, United States, 92093

Actively Recruiting

6

Veterans Affairs San Diego Healthcare System

San Diego, California, United States, 92161

Actively Recruiting

7

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20001

Actively Recruiting

8

Jacksonville Center for Clinical Research

Jacksonville, Florida, United States, 32216

Actively Recruiting

9

Radiology and Imaging Specialists

Lakeland, Florida, United States, 33801

Actively Recruiting

10

Baptist Hospital of Miami, Miami Cardiac and Vascular Institute

Miami, Florida, United States, 33176

Actively Recruiting

11

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States, 52242

Active, Not Recruiting

12

University of Louisville

Louisville, Kentucky, United States, 40202-1959

Actively Recruiting

13

Tufts Medical Center

Boston, Massachusetts, United States, 02111

Actively Recruiting

14

Henry Ford Hospital

Detroit, Michigan, United States, 48202

Withdrawn

15

University of Missouri

Columbia, Missouri, United States, 65212

Actively Recruiting

16

Newark Beth Israel Medical Center

Newark, New Jersey, United States, 07112

Actively Recruiting

17

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029-6574

Actively Recruiting

18

Feinstein Institutes for Medical Research (Staten Island University Hospital/Northwell Health)

Staten Island, New York, United States, 10305

Actively Recruiting

19

The Cleveland Clinical Foundation

Cleveland, Ohio, United States, 44106

Actively Recruiting

20

The Ohio State University

Columbus, Ohio, United States, 43210

Withdrawn

21

Oregon Health Sciences University

Portland, Oregon, United States, 97239

Actively Recruiting

22

U.S. Department of Veterans Affairs, VA Portland Health Care System

Portland, Oregon, United States, 97239

Actively Recruiting

23

Lehigh Valley Health Network

Allentown, Pennsylvania, United States, 18103

Actively Recruiting

24

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

25

Allegheny Health Network

Pittsburgh, Pennsylvania, United States, 15212

Actively Recruiting

26

Wellmont Cardiology Services

Kingsport, Tennessee, United States, 37660

Actively Recruiting

27

The University of Texas Medical Branch at Galveston

Galveston, Texas, United States, 77555

Actively Recruiting

28

Houston Methodist Research Institute

Houston, Texas, United States, 77030

Actively Recruiting

29

Sentara Hospitals

Norfolk, Virginia, United States, 23507

Actively Recruiting

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Research Team

N

Noel DeSisto

CONTACT

S

Sanjana Tabassum

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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