Actively Recruiting

Phase Not Applicable
Age: 50Years - 70Years
FEMALE
Healthy Volunteers
NCT07238478

JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women

Led by Bonafide Health · Updated on 2025-11-20

250

Participants Needed

1

Research Sites

72 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70. The primary research question is whether taking the study product daily for 12 weeks can reduce the severity and frequency of menopause-related symptoms.

CONDITIONS

Official Title

JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women

Who Can Participate

Age: 50Years - 70Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy biological females aged 50 to 70 years inclusive
  • Body mass index (BMI) between 18.5 and 34.9 kg/m2 inclusive
  • Self-reported natural postmenopause, defined as 12 months without menstrual cycle and menopausal symptoms for past 6 months
  • Self-reported moderate or severe menopause-related joint discomfort rated 5 to 9 on a 0-10 scale
  • Self-reported average of at least 4 hot flashes per day
  • In good general health and able to consume the study product
  • Agree to refrain from certain treatments during defined timeframes
  • Have reliable, stable access to Wi-Fi and a smartphone or device
  • Willing and able to consent, understand questionnaires, and complete all study procedures
Not Eligible

You will not qualify if you...

  • Lactating, pregnant, or planning pregnancy during the study
  • Currently participating in another clinical trial
  • Using treatments for menopausal or joint symptoms or other concomitant therapies as determined by the investigator
  • Known allergy or intolerance to the study product or its components
  • Use of glucosamine or chondroitin for joint symptoms in the 3 months before screening
  • Received COVID-19 vaccine within 2 weeks before screening or during the study, current COVID-19 infection, or post-COVID-19 condition
  • History of heart, kidney, liver disease, or active systemic infection such as Lyme disease, TB, or HIV
  • History of cancer (except localized skin cancer without spread) within 2 years before screening
  • Any significant disease or disorder that may affect safety or study participation as judged by the investigator
  • History or presence of gastrointestinal, liver, or kidney disease affecting drug absorption or metabolism
  • Gastrointestinal abnormalities or swallowing difficulties preventing digestion or swallowing
  • Major surgery within 3 months before screening or planned during the study
  • History of alcohol or substance abuse in past 5 years
  • Evidence of inflammatory rheumatic or autoimmune diseases
  • Chronic use of curcumin or curcuminoids supplements unless willing to undergo a 3-month washout
  • Chronic use of pain medications or analgesics for joint pain unless willing to undergo a 2-week washout
  • Severe joint or bone deformities
  • Diagnosed bone fractures
  • Candidate for surgical joint replacement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Bonafide Health

Harrison, New York, United States, 10528

Actively Recruiting

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Research Team

T

Trisha VanDusseldorp, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women | DecenTrialz