Actively Recruiting
JIT: Effect of Pain on DT in TMD
Led by University of Minnesota · Updated on 2026-02-12
160
Participants Needed
1
Research Sites
225 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.
CONDITIONS
Official Title
JIT: Effect of Pain on DT in TMD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 21 to 65 years with valid driver's license or state-issued ID
- Fluent in English to provide consent and understand study materials
- Drink at least 1 alcoholic drink on average 3 days per week for past 6 months
- Diagnosed with temporomandibular disorder (TMD) with muscle or joint pain (TMD group only)
- Own a smartphone with internet access
- Use prescription medications allowed if not contraindicating alcohol use
You will not qualify if you...
- Use of opioid painkillers within the past month
- Current major depression
- History of any psychotic disorder
- Under-controlled hypertension or diabetes
- Neurological diseases like multiple sclerosis, epilepsy, ALS, or Parkinson's
- Serious illnesses such as hepatitis or HIV/AIDS
- Impaired cognitive function
- History of substance use disorder including nicotine or tobacco
- Alcohol naive or currently trying to quit or reduce alcohol use
- Positive pregnancy test or breastfeeding or planning pregnancy
- Loss of sensation in lower leg
- Unable to complete study tasks due to weakness, immobilization, or limb loss
- Chronic pain in control group only
- Positive urine drug screen for THC, cocaine, benzodiazepines, morphine, methamphetamine
- Use of medications that contraindicate alcohol use
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55414
Actively Recruiting
Research Team
J
Jeff Boissoneault
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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