Actively Recruiting
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
Led by United States Naval Medical Center, San Diego · Updated on 2024-05-06
40
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
Sponsors
U
United States Naval Medical Center, San Diego
Lead Sponsor
N
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis. Intraarticular fractures result in a pro-inflammatory hemarthrosis that may further exacerbate the chondral damage that was sustained due to the original injury. This project will study the effect of joint lavage on the concentration of inflammatory cytokines in the ankle following a high-energy tibial pilon fracture and the resultant effect on short-term patient outcomes.
CONDITIONS
Official Title
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female age 18 years or older
- Present with an axially unstable tibial pilon fracture requiring temporary external fixation followed by delayed definitive internal fixation
- Able to give informed consent
You will not qualify if you...
- Open fractures
- Delayed presentation greater than 72 hours post-injury
- Associated talar body fracture
- Presentation after initial external fixation placement
- Unreconstructable or unsalvageable joint
- Preexisting ankle arthritis
- Previous ankle surgery
- Contralateral ankle injury
- Age less than 18 years
- Pregnant women
- Individuals who are incarcerated
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brooke Army Medical Center
Fort Sam Houston, Texas, United States, 78234
Actively Recruiting
Research Team
B
Benjamin M Wheatley, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here