Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
NCT04951947

JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer

Led by Hunan Province Tumor Hospital · Updated on 2024-09-19

30

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, single-arm phase II clinical study to evaluate the efficacy and safety of JS-201 combined with lenvatinib in the treatment of small-cell lung cancer that has failed previous chemotherapy combined with PD-L1. The primary observational endpoint is ORR, and the secondary observational endpoint is PFS, OS. The intervention mode is JS201 300mg i.v Q2w, lenvatinib 8mg po. Qd.

CONDITIONS

Official Title

JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Imaging diagnosis of extensive stage small-cell lung cancer
  • Failed first-line EC plus PD-L1 treatment
  • Performance status (PS) of 0 to 1
Not Eligible

You will not qualify if you...

  • Diagnosis of non-small cell lung cancer
  • Women who are pregnant
  • Patients with symptomatic brain metastases
  • Performance status (PS) of 2 or higher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
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Trial Site Locations

Total: 1 location

1

Hunan Cancer Hospital

Changsha, Hunan, China, 410013

Actively Recruiting

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Research Team

Y

Yongchang Zhang, MD

CONTACT

N

Nong Yang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer | DecenTrialz