Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04545957

Jump: MR Simulation For Radiation Therapy Master Protocol

Led by Brigham and Women's Hospital · Updated on 2025-07-28

86

Participants Needed

2

Research Sites

522 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.

CONDITIONS

Official Title

Jump: MR Simulation For Radiation Therapy Master Protocol

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed malignancy requiring radiation therapy
  • Age 18 years or older
  • ECOG performance status 2 or better (Karnofsky 60% or higher)
  • Ability to understand and willingness to sign written informed consent
  • Disease-specific eligibility as specified in subprotocols
Not Eligible

You will not qualify if you...

  • History of allergic reactions to gadolinium-based IV contrast if contrast will be used
  • Unable to undergo an MRI scan
  • Disease-specific exclusions as specified in subprotocols

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Brigham and Women Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

2

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

R

Raymond Mak, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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