Actively Recruiting

Age: 10Years - 35Years
All Genders
NCT06883396

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Led by Hospital for Special Surgery, New York · Updated on 2026-02-13

850

Participants Needed

16

Research Sites

256 weeks

Total Duration

On this page

Sponsors

H

Hospital for Special Surgery, New York

Lead Sponsor

A

American Orthopaedic Society for Sports Medicine

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are: * What are the risk factors for recurrent patellar instability after MPFL reconstruction? * What functional outcomes do patients report after MPFL reconstruction? Participants undergoing MPFL reconstruction will answer survey questions about their knee and activity level 1 year and 2 years after surgery.

CONDITIONS

Official Title

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Who Can Participate

Age: 10Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 10-35 years old
  • Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises
Not Eligible

You will not qualify if you...

  • Previous ipsilateral knee surgery
  • Obligatory/fixed/habitual patella dislocation or subluxation
  • Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes
  • Pathologic tibiofemoral instability

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 16 locations

1

Stanford University

Redwood City, California, United States, 94063

Actively Recruiting

2

University of Florida

Gainesville, Florida, United States, 32607

Actively Recruiting

3

Midwest Orthopaedics at Rush

Chicago, Illinois, United States, 60612

Actively Recruiting

4

University of Iowa

Iowa City, Iowa, United States, 52242

Actively Recruiting

5

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

6

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

7

Mayo Clinic

Rochester, Minnesota, United States, 55905

Not Yet Recruiting

8

Mount Sinai

New York, New York, United States, 10012

Not Yet Recruiting

9

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

10

Hospital for Special Surgery

New York, New York, United States, 10021

Actively Recruiting

11

Duke Health

Wake Forest, North Carolina, United States, 27587

Actively Recruiting

12

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States, 45229

Actively Recruiting

13

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Not Yet Recruiting

14

Ohio State University Wexler Medical Center

Dublin, Ohio, United States, 43016

Actively Recruiting

15

Oregon Health & Science University

Portland, Oregon, United States, 97239

Actively Recruiting

16

Scottish Rite for Children

Dallas, Texas, United States, 75219

Actively Recruiting

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Research Team

S

Simone Gruber

CONTACT

N

Natalie Pahapill

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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