Actively Recruiting
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
Led by Sam Tyagi · Updated on 2025-10-20
30
Participants Needed
1
Research Sites
346 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).
CONDITIONS
Official Title
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing to give informed consent
- Scheduled for elective thoracic aorta repair or thoracoabdominal aortic repair
- Requires naloxone continuous infusion for spinal prophylaxis
You will not qualify if you...
- Allergy to ketamine, acetaminophen, or fentanyl
- Diagnosis of schizophrenia
- History of hydrocephalus or central nervous system mass
- Incarcerated individuals
- Pregnant or lactating individuals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kentucky Medical Center
Lexington, Kentucky, United States, 40536
Actively Recruiting
Research Team
E
Eric Johnson, PharmD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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